diff --git a/pkgs/games/fallout-ce/build.nix b/pkgs/games/fallout-ce/build.nix
index 58305487d7c1..5f0c0b404f36 100644
--- a/pkgs/games/fallout-ce/build.nix
+++ b/pkgs/games/fallout-ce/build.nix
@@ -7,6 +7,7 @@
 
 , extraBuildInputs ? [ ]
 , extraMeta
+, patches
 , pname
 , version
 , src
@@ -45,7 +46,7 @@ let
   '';
 in
 stdenv.mkDerivation {
-  inherit pname version src;
+  inherit pname version src patches;
 
   nativeBuildInputs = [ cmake ];
   buildInputs = [ SDL2 ] ++ extraBuildInputs;
diff --git a/pkgs/games/fallout-ce/fallout-ce.nix b/pkgs/games/fallout-ce/fallout-ce.nix
index 2053738d1df2..2c30d62bb77f 100644
--- a/pkgs/games/fallout-ce/fallout-ce.nix
+++ b/pkgs/games/fallout-ce/fallout-ce.nix
@@ -1,5 +1,6 @@
 { callPackage
 , fetchFromGitHub
+, fetchpatch2
 }:
 
 callPackage ./build.nix rec {
@@ -13,6 +14,14 @@ callPackage ./build.nix rec {
     hash = "sha256-ZiBoF3SL00sN0QrD3fkWG9SAknumOvzRB1oQJff6ITA=";
   };
 
+  patches = [
+    # Fix case-sensitive filesystems issue when save/load games
+    (fetchpatch2 {
+      url = "https://github.com/alexbatalov/fallout1-ce/commit/aa3c5c1e3e3f9642d536406b2d8d6b362c9e402f.patch";
+      sha256 = "sha256-quFRbKMS2pNDCNTWc1ZoB3jnB5qzw0b+2OeJUi8IPBc=";
+    })
+  ];
+
   extraMeta = {
     description = "Fully working re-implementation of Fallout, with the same original gameplay, engine bugfixes, and some quality of life improvements";
     homepage = "https://github.com/alexbatalov/fallout1-ce";
diff --git a/pkgs/games/fallout-ce/fallout2-ce.nix b/pkgs/games/fallout-ce/fallout2-ce.nix
index b9d41ad994c2..09dbd93feb9d 100644
--- a/pkgs/games/fallout-ce/fallout2-ce.nix
+++ b/pkgs/games/fallout-ce/fallout2-ce.nix
@@ -1,5 +1,6 @@
 { callPackage
 , fetchFromGitHub
+, fetchpatch2
 , zlib
 }:
 
@@ -14,6 +15,14 @@ callPackage ./build.nix rec {
     hash = "sha256-r1pnmyuo3uw2R0x9vGScSHIVNA6t+txxABzgHkUEY5U=";
   };
 
+  patches = [
+    # Fix case-sensitive filesystems issue when save/load games
+    (fetchpatch2 {
+      url = "https://github.com/alexbatalov/fallout2-ce/commit/d843a662b3ceaf01ac363e9abb4bfceb8b805c36.patch";
+      sha256 = "sha256-u4E9+DE6sGYikIGwKDmSBj3ErCfIo6YzIw2eMiqXw/E=";
+    })
+  ];
+
   extraBuildInputs = [ zlib ];
 
   extraMeta = {