diff --git a/pkgs/development/python-modules/poppler-qt5/default.nix b/pkgs/development/python-modules/poppler-qt5/default.nix
index 345f092a80fa..94d86f7b7133 100644
--- a/pkgs/development/python-modules/poppler-qt5/default.nix
+++ b/pkgs/development/python-modules/poppler-qt5/default.nix
@@ -1,44 +1,64 @@
-{ buildPythonPackage, fetchPypi, lib, sip, qtbase, pyqt5, poppler, pkg-config, fetchpatch
-, substituteAll
+{ stdenv
+, lib
+, buildPythonPackage
+, isPy3k
+, fetchPypi
+, pythonPackages
+, sip_5
+, qtbase
+, qmake
+, pyqt5
+, pyqt-builder
+, poppler
+, pkg-config
+, fetchpatch
 }:
 
 buildPythonPackage rec {
   pname = "python-poppler-qt5";
-  version = "0.24.2";
+  version = "21.1.0";
+
+  disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0l69llw1fzwz8y90q0qp9q5pifbrqjjbwii7di54dwghw5fc6w1r";
+    sha256 = "0b82gm4i75q5v19kfbq0h4y0b2vcwr2213zkhxh6l0h45kdndmxd";
   };
 
   patches = [
-    (substituteAll {
-      src = ./poppler-include-dir.patch;
-      poppler_include_dir = "${poppler.dev}/include/poppler";
-    })
+    # Fix for https://github.com/frescobaldi/python-poppler-qt5/issues/43 (from PR #45)
     (fetchpatch {
-      url = "https://github.com/wbsoft/python-poppler-qt5/commit/faf4d1308f89560b0d849671226e3080dfc72e79.patch";
-      sha256 = "18krhh6wzsnpxzlzv02nginb1vralla8ai24zqk10nc4mj6fkj86";
+      url = "https://github.com/frescobaldi/python-poppler-qt5/commit/40e71ad88173d02648bceb2438bc0567e60dacd5.patch";
+      sha256 = "0c93d0k7b1n2s2njl8g92x6vw3z96da1fczah9qx07x08iw8dzi5";
     })
   ];
 
-  setupPyBuildFlags = [
-    "--pyqt-sip-dir ${pyqt5}/share/sip/PyQt5"
-    "--qt-include-dir ${qtbase.dev}/include"
-  ];
+  buildInputs = [ qtbase.dev poppler pyqt-builder ];
+  nativeBuildInputs = [ pkg-config qmake sip_5 ];
+  propagatedBuildInputs = [ pyqt5.dev ];
 
-  buildInputs = [ qtbase.dev poppler ];
-  nativeBuildInputs = [ pkg-config ];
-  propagatedBuildInputs = [ sip pyqt5.dev ];
+  format = "pyproject";
+  dontConfigure = true;
+
+  postPatch = ''
+    cat <<EOF >> pyproject.toml
+    sip-include-dirs = ["${pyqt5}/share/sip/PyQt5"]
+
+    [tool.sip.bindings.Poppler-Qt5]
+    include-dirs = ["${poppler.dev}/include/poppler"]
+    tags = ["${sip_5.platform_tag}"]
+    EOF
+  '';
 
   # no tests, just bindings for `poppler_qt5`
   doCheck = false;
+  pythonImportsCheck = [ "popplerqt5" ];
 
   dontWrapQtApps = true;
 
   meta = with lib; {
-    homepage = "https://github.com/wbsoft/python-poppler-qt5";
-    license = licenses.gpl2;
-    maintainers = with maintainers; [ ];
+    homepage = "https://github.com/frescobaldi/python-poppler-qt5";
+    license = licenses.lgpl21Plus;
+    maintainers = with maintainers; [ eduardosm ];
   };
 }
diff --git a/pkgs/development/python-modules/poppler-qt5/poppler-include-dir.patch b/pkgs/development/python-modules/poppler-qt5/poppler-include-dir.patch
deleted file mode 100644
index 7106c1d6352c..000000000000
--- a/pkgs/development/python-modules/poppler-qt5/poppler-include-dir.patch
+++ /dev/null
@@ -1,12 +0,0 @@
-diff --git a/setup.py b/setup.py
-index 59a75b0..0a73268 100644
---- a/setup.py
-+++ b/setup.py
-@@ -169,6 +169,7 @@ class build_ext(build_ext_base):
-                              'Please specify via --pyqt-sip-flags=')
- 
-         self.include_dirs += (self.qt_include_dir,
-+                              '@poppler_include_dir@',
-                               os.path.join(self.qt_include_dir, 'QtCore'),
-                               os.path.join(self.qt_include_dir, 'QtGui'),
-                               os.path.join(self.qt_include_dir, 'QtXml'))
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index b0e7729140ad..330f93703e88 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5077,7 +5077,7 @@ in {
   poolsense = callPackage ../development/python-modules/poolsense { };
 
   poppler-qt5 = callPackage ../development/python-modules/poppler-qt5 {
-    inherit (pkgs.qt5) qtbase;
+    inherit (pkgs.qt5) qtbase qmake;
     inherit (pkgs.libsForQt5) poppler;
   };