diff --git a/pkgs/development/python-modules/keystone-engine/default.nix b/pkgs/development/python-modules/keystone-engine/default.nix
new file mode 100644
index 000000000000..ed9f3a6bb702
--- /dev/null
+++ b/pkgs/development/python-modules/keystone-engine/default.nix
@@ -0,0 +1,28 @@
+{ lib, buildPythonPackage, fetchPypi, keystone }:
+
+buildPythonPackage rec {
+  pname = "keystone-engine";
+  version = "0.9.2";
+
+  src = fetchPypi {
+   inherit pname version;
+   sha256 = "1xahdr6bh3dw5swrc2r8kqa8ljhqlb7k2kxv5mrw5rhcmcnzcyig";
+  };
+
+  preConfigure = ''
+    substituteInPlace setup.py --replace \
+      "libkeystone" "${keystone}/lib/libkeystone"
+  '';
+
+  # No tests
+  doCheck = false;
+
+  pythonImportsCheck = [ "keystone" ];
+
+  meta = with lib; {
+    description = "Lightweight multi-platform, multi-architecture assembler framework";
+    homepage = "https://www.keystone-engine.org";
+    maintainers = with maintainers; [ dump_stack ];
+    license = licenses.gpl2Only;
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 507f0019171b..2e344fde7dff 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -3479,6 +3479,8 @@ in {
 
   keyrings-alt = callPackage ../development/python-modules/keyrings-alt { };
 
+  keystone-engine = callPackage ../development/python-modules/keystone-engine { };
+
   keyutils = callPackage ../development/python-modules/keyutils { inherit (pkgs) keyutils; };
 
   kicad = disabledIf isPy27 (toPythonModule (pkgs.kicad.override { python3 = python; }).src);