diff --git a/pkgs/development/python-modules/cypari2/default.nix b/pkgs/development/python-modules/cypari2/default.nix
new file mode 100644
index 000000000000..fc3c311a5061
--- /dev/null
+++ b/pkgs/development/python-modules/cypari2/default.nix
@@ -0,0 +1,55 @@
+{ stdenv
+, bootstrapped-pip
+, buildPythonPackage
+, python
+, fetchPypi
+, pari
+, gmp
+, cython
+, cysignals
+, six
+}:
+
+buildPythonPackage rec {
+  pname = "cypari2";
+  version = "1.1.4"; # remove six dependency on upgrade to >1.1.4
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "0n0mp8qmvvzmfaawg39d3mkyzf65q2zkz7bnqyk4sfjbz4xwc6mb";
+  };
+
+  # This differs slightly from the default python installPhase in that it pip-installs
+  # "." instead of "*.whl".
+  # That is because while the default install phase succeeds to build the package,
+  # it fails to generate the file "auto_paridecl.pxd".
+  installPhase = ''
+    mkdir -p "$out/lib/${python.libPrefix}/site-packages"
+    export PYTHONPATH="$out/lib/${python.libPrefix}/site-packages:$PYTHONPATH"
+
+    # install "." instead of "*.whl"
+    ${bootstrapped-pip}/bin/pip install --no-index --prefix=$out --no-cache --build=tmpdir .
+  '';
+
+  buildInputs = [
+    pari
+    gmp
+  ];
+
+  propagatedBuildInputs = [
+    cysignals
+    cython
+    six # after 1.1.4: will not be needed
+  ];
+
+  checkPhase = ''
+    make check
+  '';
+
+  meta = with stdenv.lib; {
+    description = "Cython bindings for PARI";
+    license = licenses.gpl2;
+    maintainers = with maintainers; [ timokau ];
+    homepage = https://github.com/defeo/cypari2;
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index f0ffadc82d1b..5b1877875344 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1190,6 +1190,8 @@ in {
 
   cysignals = callPackage ../development/python-modules/cysignals { };
 
+  cypari2 = callPackage ../development/python-modules/cypari2 { };
+
   dlib = buildPythonPackage rec {
     inherit (pkgs.dlib) name src nativeBuildInputs meta;