diff --git a/pkgs/development/perl-modules/Tirex/default.nix b/pkgs/development/perl-modules/Tirex/default.nix
index 655610e898f2..48e63bb5932c 100644
--- a/pkgs/development/perl-modules/Tirex/default.nix
+++ b/pkgs/development/perl-modules/Tirex/default.nix
@@ -7,6 +7,7 @@
 , JSON
 , LWP
 , mapnik
+, boost
 , nix-update-script
 }:
 
@@ -22,11 +23,18 @@ buildPerlPackage rec {
   };
 
   patches = [
+    # Support Mapnik >= v4.0.0 (`mapnik/box2d.hpp` -> `mapnik/geometry/box2d.hpp`)
     # https://github.com/openstreetmap/tirex/pull/54
     (fetchpatch {
-      url = "https://github.com/openstreetmap/tirex/commit/da0c5db926bc0939c53dd902a969b689ccf9edde.patch";
+      url = "https://github.com/openstreetmap/tirex/commit/5f131231c9c12e88793afba471b150ca8af8d587.patch";
       hash = "sha256-bnL1ZGy8ZNSZuCRbZn59qRVLg3TL0GjFYnhRKroeVO0=";
     })
+    # Support Mapnik >= v4.0.0 (boost:filesystem no longer indirectly linked)
+    # https://github.com/openstreetmap/tirex/pull/59
+    (fetchpatch {
+      url = "https://github.com/openstreetmap/tirex/commit/137903be9b7b35dde4c7010e65faa16bcf6ad476.patch";
+      hash = "sha256-JDqwWVnzExPwLpzv4LbSmGYah956uko+Zdicahua9oQ=";
+    })
   ];
 
   buildInputs = [
@@ -35,6 +43,7 @@ buildPerlPackage rec {
     JSON
     LWP
     mapnik
+    boost
   ] ++ mapnik.buildInputs;
 
   installPhase = ''