diff --git a/pkgs/development/compilers/ocaml/5.0.nix b/pkgs/development/compilers/ocaml/5.0.nix
new file mode 100644
index 000000000000..a36b3e31a427
--- /dev/null
+++ b/pkgs/development/compilers/ocaml/5.0.nix
@@ -0,0 +1,9 @@
+import ./generic.nix {
+  major_version = "5";
+  minor_version = "0";
+  patch_version = "0-beta1";
+  src = fetchTarball {
+    url = "https://caml.inria.fr/pub/distrib/ocaml-5.0/ocaml-5.0.0~beta1.tar.xz";
+    sha256 = "sha256:1kwb53ra5qbwiiyrx5da7l5mqkjf0fr3rqgkrm3wr83l25scimj4";
+  };
+}
diff --git a/pkgs/development/compilers/ocaml/generic.nix b/pkgs/development/compilers/ocaml/generic.nix
index 2c6045c13a62..7db0eca0ee4d 100644
--- a/pkgs/development/compilers/ocaml/generic.nix
+++ b/pkgs/development/compilers/ocaml/generic.nix
@@ -73,6 +73,7 @@ stdenv.mkDerivation (args // {
   configurePlatforms = lib.optionals (lib.versionAtLeast version "4.08" && !(stdenv.isDarwin && stdenv.isAarch64)) [ "host" "target" ];
   # x86_64-unknown-linux-musl-ld: -r and -pie may not be used together
   hardeningDisable = lib.optional (lib.versionAtLeast version "4.09" && stdenv.hostPlatform.isMusl) "pie"
+    ++ lib.optional (lib.versionAtLeast version "5.0" && stdenv.cc.isClang) "strictoverflow"
     ++ lib.optionals (args ? hardeningDisable) args.hardeningDisable;
 
   # Older versions have some race:
diff --git a/pkgs/top-level/ocaml-packages.nix b/pkgs/top-level/ocaml-packages.nix
index d8250fc8aa80..deb76032f6a2 100644
--- a/pkgs/top-level/ocaml-packages.nix
+++ b/pkgs/top-level/ocaml-packages.nix
@@ -1663,6 +1663,8 @@ in let inherit (pkgs) callPackage; in rec
 
   ocamlPackages_4_14 = mkOcamlPackages (callPackage ../development/compilers/ocaml/4.14.nix { });
 
+  ocamlPackages_5_0 = mkOcamlPackages (callPackage ../development/compilers/ocaml/5.0.nix { });
+
   ocamlPackages_latest = ocamlPackages_4_14;
 
   ocamlPackages = ocamlPackages_4_14;