diff --git a/pkgs/applications/editors/emacs/generic.nix b/pkgs/applications/editors/emacs/generic.nix
index 69bb51e10f20..9a19fb787e12 100644
--- a/pkgs/applications/editors/emacs/generic.nix
+++ b/pkgs/applications/editors/emacs/generic.nix
@@ -11,7 +11,7 @@
 , libtiff, librsvg, gconf, libxml2, imagemagick, gnutls, libselinux
 , alsaLib, cairo, acl, gpm, AppKit, GSS, ImageIO, m17n_lib, libotf
 , jansson, harfbuzz
-, libgccjit, targetPlatform, binutils, binutils-unwrapped, makeWrapper # native-comp params
+, libgccjit, targetPlatform, makeWrapper # native-comp params
 , systemd ? null
 , withX ? !stdenv.isDarwin
 , withNS ? stdenv.isDarwin
@@ -67,18 +67,23 @@ in stdenv.mkDerivation {
 
     # Make native compilation work both inside and outside of nix build
     (lib.optionalString nativeComp (let
-      libPath = lib.concatStringsSep ":" [
-        "${lib.getLib libgccjit}/lib/gcc/${targetPlatform.config}/${libgccjit.version}"
-        "${lib.getLib stdenv.cc.cc}/lib"
-        "${lib.getLib stdenv.glibc}/lib"
-      ];
+      backendPath = (lib.concatStringsSep " "
+        (builtins.map (x: ''\"-B${x}\"'') [
+          # Paths necessary so the JIT compiler finds its libraries:
+          "${lib.getLib libgccjit}/lib"
+          "${lib.getLib libgccjit}/lib/gcc"
+          "${lib.getLib stdenv.cc.libc}/lib"
+
+          # Executable paths necessary for compilation (ld, as):
+          "${lib.getBin stdenv.cc.cc}"
+          "${lib.getBin stdenv.cc.bintools}"
+          "${lib.getBin stdenv.cc.bintools.bintools}"
+        ]));
     in ''
       substituteInPlace lisp/emacs-lisp/comp.el --replace \
-        "(defcustom comp-async-env-modifier-form nil" \
-        "(defcustom comp-async-env-modifier-form '((setenv \"LIBRARY_PATH\" (string-join (seq-filter (lambda (v) (null (eq v nil))) (list (getenv \"LIBRARY_PATH\") \"${libPath}\")) \":\")))"
-
+        "(defcustom comp-native-driver-options nil" \
+        "(defcustom comp-native-driver-options '(${backendPath})"
     ''))
-
     ""
   ];
 
@@ -156,11 +161,6 @@ in stdenv.mkDerivation {
         "$out/bin/emacs"
       patchelf --add-needed "libXcursor.so.1" "$out/bin/emacs"
     '')
-
-    (lib.optionalString nativeComp ''
-      wrapProgram $out/bin/emacs-* --prefix PATH : "${lib.makeBinPath [ binutils binutils-unwrapped ]}"
-    '')
-
   ];
 
   passthru = {
diff --git a/pkgs/development/compilers/gcc/9/default.nix b/pkgs/development/compilers/gcc/9/default.nix
index 7cfc977b3f4c..305ed56df78c 100644
--- a/pkgs/development/compilers/gcc/9/default.nix
+++ b/pkgs/development/compilers/gcc/9/default.nix
@@ -184,7 +184,7 @@ stdenv.mkDerivation ({
 
   preConfigure = import ../common/pre-configure.nix {
     inherit (stdenv) lib;
-    inherit version hostPlatform gnatboot langAda langGo;
+    inherit version hostPlatform gnatboot langAda langGo langJit;
   };
 
   dontDisableStatic = true;
diff --git a/pkgs/development/compilers/gcc/builder.sh b/pkgs/development/compilers/gcc/builder.sh
index d242f1a822cd..2204744a4b59 100644
--- a/pkgs/development/compilers/gcc/builder.sh
+++ b/pkgs/development/compilers/gcc/builder.sh
@@ -261,7 +261,7 @@ postInstall() {
     fi
 
     if type "install_name_tool"; then
-        for i in "${!outputLib}"/lib/*.*.dylib; do
+        for i in "${!outputLib}"/lib/*.*.dylib "${!outputLib}"/lib/*.so.[0-9]; do
             install_name_tool -id "$i" "$i" || true
             for old_path in $(otool -L "$i" | grep "$out" | awk '{print $1}'); do
               new_path=`echo "$old_path" | sed "s,$out,${!outputLib},"`
diff --git a/pkgs/development/compilers/gcc/common/pre-configure.nix b/pkgs/development/compilers/gcc/common/pre-configure.nix
index fff490148007..1c65b4a8ba64 100644
--- a/pkgs/development/compilers/gcc/common/pre-configure.nix
+++ b/pkgs/development/compilers/gcc/common/pre-configure.nix
@@ -2,6 +2,7 @@
 , gnatboot ? null
 , langAda ? false
 , langJava ? false
+, langJit ? false
 , langGo }:
 
 assert langJava -> lib.versionOlder version "7";
@@ -49,3 +50,11 @@ lib.optionalString (hostPlatform.isSunOS && hostPlatform.is64bit) ''
 + lib.optionalString (hostPlatform.isDarwin) ''
   export ac_cv_func_aligned_alloc=no
 ''
+
+# In order to properly install libgccjit on macOS Catalina, strip(1)
+# upon installation must not remove external symbols, otherwise the
+# install step errors with "symbols referenced by indirect symbol
+# table entries that can't be stripped".
++ lib.optionalString (hostPlatform.isDarwin && langJit) ''
+  export STRIP='strip -x'
+''