diff --git a/pkgs/applications/science/biology/exonerate/default.nix b/pkgs/applications/science/biology/exonerate/default.nix
new file mode 100644
index 000000000000..1dd6b44692a3
--- /dev/null
+++ b/pkgs/applications/science/biology/exonerate/default.nix
@@ -0,0 +1,25 @@
+{ stdenv, fetchurl, glib, pkgconfig }:
+
+stdenv.mkDerivation rec {
+  version = "2.4.0";
+  pname = "exonerate";
+
+  src = fetchurl {
+    url = "http://ftp.ebi.ac.uk/pub/software/vertebrategenomics/exonerate/${pname}-${version}.tar.gz";
+    sha256 = "0hj0m9xygiqsdxvbg79wq579kbrx1mdrabi2bzqz2zn9qwfjcjgq";
+  };
+
+  doCheck = true;
+
+  buildInputs = [ glib ];
+
+  nativeBuildInputs = [ pkgconfig ];
+
+  meta = with stdenv.lib; {
+    description = "Generic tool for sequence alignment";
+    homepage = https://www.ebi.ac.uk/about/vertebrate-genomics/software/exonerate;
+    license = licenses.gpl3;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix ;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 33464ab30a45..1757d3100c19 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -21642,6 +21642,8 @@ in
 
   ezminc = callPackage ../applications/science/biology/EZminc { };
 
+  exonerate = callPackage ../applications/science/biology/exonerate { };
+
   hisat2 = callPackage ../applications/science/biology/hisat2 { };
 
   htslib = callPackage ../development/libraries/science/biology/htslib { };