diff --git a/pkgs/applications/radio/pothos/default.nix b/pkgs/applications/radio/pothos/default.nix
index 1b36b36829a0..6691ffe2dd45 100644
--- a/pkgs/applications/radio/pothos/default.nix
+++ b/pkgs/applications/radio/pothos/default.nix
@@ -1,6 +1,7 @@
 { lib
 , mkDerivation
 , fetchFromGitHub
+, fetchpatch
 , cmake
 , pkg-config
 , doxygen
@@ -33,6 +34,12 @@ mkDerivation rec {
   patches = [
     # spuce's CMakeLists.txt uses QT5_USE_Modules, which does not seem to work on Nix
     ./spuce.patch
+    # Poco had some breaking API changes in 1.12
+    (fetchpatch {
+      name = "poco-1.12-compat.patch";
+      url = "https://github.com/pothosware/PothosCore/commit/092d1209b0fd0aa8a1733706c994fa95e66fd017.patch";
+      hash = "sha256-bZXG8kD4+1LgDV8viZrJ/DMjg8UvW7b5keJQDXurfkA=";
+    })
   ];
 
   nativeBuildInputs = [ cmake pkg-config doxygen wrapQtAppsHook ];