diff --git a/pkgs/applications/science/biology/ants/default.nix b/pkgs/applications/science/biology/ants/default.nix
index e117af03b57d..4c5f3162febd 100644
--- a/pkgs/applications/science/biology/ants/default.nix
+++ b/pkgs/applications/science/biology/ants/default.nix
@@ -1,18 +1,18 @@
-{ lib, stdenv, fetchFromGitHub, cmake, makeWrapper, itk, vtk_8, Cocoa }:
+{ lib, stdenv, fetchFromGitHub, cmake, makeWrapper, itk, vtk, Cocoa }:
 
 stdenv.mkDerivation rec {
-  pname    = "ANTs";
+  pname = "ANTs";
   version = "2.4.3";
 
   src = fetchFromGitHub {
     owner  = "ANTsX";
     repo   = "ANTs";
-    rev    = "v${version}";
+    rev    = "refs/tags/v${version}";
     sha256 = "sha256-S4HYhsqof27UXEYjKvbod8N7PkZDmwLdwcEAvJD0W5g=";
   };
 
   nativeBuildInputs = [ cmake makeWrapper ];
-  buildInputs = [ itk vtk_8 ] ++ lib.optionals stdenv.isDarwin [ Cocoa ];
+  buildInputs = [ itk vtk ] ++ lib.optionals stdenv.isDarwin [ Cocoa ];
 
   cmakeFlags = [ "-DANTS_SUPERBUILD=FALSE" "-DUSE_VTK=TRUE" ];
 
diff --git a/pkgs/development/libraries/itk/generic.nix b/pkgs/development/libraries/itk/generic.nix
index 157ae89b7ebc..78f4d56bfac6 100644
--- a/pkgs/development/libraries/itk/generic.nix
+++ b/pkgs/development/libraries/itk/generic.nix
@@ -1,7 +1,7 @@
 { version, rev, sourceSha256 }:
 
 { lib, stdenv, fetchFromGitHub, cmake, makeWrapper
-, pkg-config, libX11, libuuid, xz, vtk_8, Cocoa }:
+, pkg-config, libX11, libuuid, xz, vtk, Cocoa }:
 
 stdenv.mkDerivation rec {
   pname = "itk";
@@ -53,7 +53,15 @@ stdenv.mkDerivation rec {
   ];
 
   nativeBuildInputs = [ cmake xz makeWrapper ];
-  buildInputs = [ libX11 libuuid vtk_8 ] ++ lib.optionals stdenv.isDarwin [ Cocoa ];
+  buildInputs = [ libX11 libuuid vtk ] ++ lib.optionals stdenv.isDarwin [ Cocoa ];
+  # Due to ITKVtkGlue=ON and the additional dependencies needed to configure VTK 9
+  # (specifically libGL and libX11 on Linux),
+  # it's now seemingly necessary for packages that configure ITK to
+  # also include configuration deps of VTK, even if VTK is not required or available.
+  # These deps were propagated from VTK 9 in https://github.com/NixOS/nixpkgs/pull/206935,
+  # so we simply propagate them again from ITK.
+  # This admittedly is a hack and seems like an issue with VTK 9's CMake configuration.
+  propagatedBuildInputs = vtk.propagatedBuildInputs;
 
   postInstall = ''
     wrapProgram "$out/bin/h5c++" --prefix PATH ":" "${pkg-config}/bin"