diff --git a/pkgs/development/python-modules/pygame-ce/default.nix b/pkgs/development/python-modules/pygame-ce/default.nix
new file mode 100644
index 000000000000..a476ecd58b85
--- /dev/null
+++ b/pkgs/development/python-modules/pygame-ce/default.nix
@@ -0,0 +1,123 @@
+{ stdenv
+, lib
+, substituteAll
+, fetchFromGitHub
+, buildPythonPackage
+, pythonOlder
+, python
+, pkg-config
+, setuptools
+, cython
+
+, AppKit
+, fontconfig
+, freetype
+, libjpeg
+, libpng
+, libX11
+, portmidi
+, SDL2
+, SDL2_image
+, SDL2_mixer
+, SDL2_ttf
+}:
+
+buildPythonPackage rec {
+  pname = "pygame-ce";
+  version = "2.4.1";
+  pyproject = true;
+
+  disabled = pythonOlder "3.6";
+
+  src = fetchFromGitHub {
+    owner = "pygame-community";
+    repo = "pygame-ce";
+    rev = "refs/tags/${version}";
+    hash = "sha256-4Ky+QEUsQ0odcwEETk0yGECs7CcJQthhavboOnMDvF8=";
+    # Unicode file cause different checksums on HFS+ vs. other filesystems
+    postFetch = "rm -rf $out/docs/reST";
+  };
+
+  patches = [
+    (substituteAll {
+      src = ./fix-dependency-finding.patch;
+      buildinputs_include = builtins.toJSON (builtins.concatMap (dep: [
+        "${lib.getDev dep}/"
+        "${lib.getDev dep}/include"
+        "${lib.getDev dep}/include/SDL2"
+      ]) buildInputs);
+      buildinputs_lib = builtins.toJSON (builtins.concatMap (dep: [
+        "${lib.getLib dep}/"
+        "${lib.getLib dep}/lib"
+      ]) buildInputs);
+    })
+    # Skip tests that should be disabled without video driver
+    ./skip-surface-tests.patch
+  ];
+
+  postPatch = ''
+    substituteInPlace buildconfig/config_{unix,darwin}.py \
+      --replace-fail 'from distutils' 'from setuptools._distutils'
+    substituteInPlace src_py/sysfont.py \
+      --replace-fail 'path="fc-list"' 'path="${fontconfig}/bin/fc-list"' \
+      --replace-fail /usr/X11/bin/fc-list ${fontconfig}/bin/fc-list
+  '' + lib.optionalString stdenv.isDarwin ''
+    # flaky
+    rm test/system_test.py
+  '';
+
+  nativeBuildInputs = [
+    pkg-config
+    cython
+    setuptools
+  ];
+
+  buildInputs = [
+    freetype
+    libX11
+    libjpeg
+    libpng
+    portmidi
+    SDL2
+    SDL2_image
+    SDL2_mixer
+    SDL2_ttf
+  ] ++ lib.optionals stdenv.isDarwin [
+    AppKit
+  ];
+
+  preConfigure = ''
+    ${python.pythonOnBuildForHost.interpreter} buildconfig/config.py
+  '';
+
+  env = {
+    SDL_CONFIG = "${SDL2.dev}/bin/sdl2-config";
+  } // lib.optionalAttrs stdenv.cc.isClang {
+    NIX_CFLAGS_COMPILE = "-Wno-error=incompatible-function-pointer-types";
+  };
+
+  preCheck = ''
+    export HOME=$(mktemp -d)
+    # No audio or video device in test environment
+    export SDL_VIDEODRIVER=dummy
+    export SDL_AUDIODRIVER=disk
+  '';
+
+  checkPhase = ''
+    runHook preCheck
+    ${python.interpreter} -m pygame.tests -v --exclude opengl,timing --time_out 300
+    runHook postCheck
+  '';
+
+  pythonImportsCheck = [
+    "pygame"
+  ];
+
+  meta = with lib; {
+    description = "Pygame Community Edition (CE) - library for multimedia application built on SDL";
+    homepage = "https://pyga.me/";
+    license = licenses.lgpl21Plus;
+    maintainers = with maintainers; [ pbsds ];
+    platforms = platforms.unix;
+  };
+}
diff --git a/pkgs/development/python-modules/pygame-ce/fix-dependency-finding.patch b/pkgs/development/python-modules/pygame-ce/fix-dependency-finding.patch
new file mode 100644
index 000000000000..5e39dff13575
--- /dev/null
+++ b/pkgs/development/python-modules/pygame-ce/fix-dependency-finding.patch
@@ -0,0 +1,41 @@
+diff --git a/buildconfig/config_darwin.py b/buildconfig/config_darwin.py
+index 9503ea70..d0d3ab6e 100644
+--- a/buildconfig/config_darwin.py
++++ b/buildconfig/config_darwin.py
+@@ -140,16 +140,8 @@ def main(auto_config=False):
+     ])
+ 
+     print('Hunting dependencies...')
+-    incdirs = ['/usr/local/include', '/opt/homebrew/include']
+-    incdirs.extend(['/usr/local/include/SDL2', '/opt/homebrew/include/SDL2', '/opt/local/include/SDL2'])
+-
+-    incdirs.extend([
+-       #'/usr/X11/include',
+-       '/opt/local/include',
+-       '/opt/local/include/freetype2/freetype']
+-    )
+-    #libdirs = ['/usr/local/lib', '/usr/X11/lib', '/opt/local/lib']
+-    libdirs = ['/usr/local/lib', '/opt/local/lib', '/opt/homebrew/lib']
++    incdirs = @buildinputs_include@
++    libdirs = @buildinputs_lib@
+ 
+     for d in DEPS:
+         if isinstance(d, (list, tuple)):
+diff --git a/buildconfig/config_unix.py b/buildconfig/config_unix.py
+index 3eba5b5c..53cc6233 100644
+--- a/buildconfig/config_unix.py
++++ b/buildconfig/config_unix.py
+@@ -240,11 +240,8 @@ def main(auto_config=False):
+     if not DEPS[0].found:
+         raise RuntimeError('Unable to run "sdl-config". Please make sure a development version of SDL is installed.')
+ 
+-    incdirs = []
+-    libdirs = []
+-    for extrabase in extrabases:
+-        incdirs += [extrabase + d for d in origincdirs]
+-        libdirs += [extrabase + d for d in origlibdirs]
++    incdirs = @buildinputs_include@
++    libdirs = @buildinputs_lib@
+ 
+     for arg in DEPS[0].cflags.split():
+         if arg[:2] == '-I':
diff --git a/pkgs/development/python-modules/pygame-ce/skip-surface-tests.patch b/pkgs/development/python-modules/pygame-ce/skip-surface-tests.patch
new file mode 100644
index 000000000000..21d9c9060f3b
--- /dev/null
+++ b/pkgs/development/python-modules/pygame-ce/skip-surface-tests.patch
@@ -0,0 +1,26 @@
+diff --git a/test/surface_test.py b/test/surface_test.py
+index 5ce78b6e..8b8f7ed5 100644
+--- a/test/surface_test.py
++++ b/test/surface_test.py
+@@ -1091,6 +1091,10 @@ class GeneralSurfaceTests(unittest.TestCase):
+         finally:
+             pygame.display.quit()
+ 
++    @unittest.skipIf(
++        os.environ.get("SDL_VIDEODRIVER") == "dummy",
++        'requires a non-"dummy" SDL_VIDEODRIVER',
++    )
+     def test_convert_init(self):
+         """Ensure initialization exceptions are raised
+         for surf.convert()."""
+@@ -1118,6 +1122,10 @@ class GeneralSurfaceTests(unittest.TestCase):
+         finally:
+             pygame.display.quit()
+ 
++    @unittest.skipIf(
++        os.environ.get("SDL_VIDEODRIVER") == "dummy",
++        'requires a non-"dummy" SDL_VIDEODRIVER',
++    )
+     def test_convert_alpha_init(self):
+         """Ensure initialization exceptions are raised
+         for surf.convert_alpha()."""
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 8ba934720ea5..133f2c61afb7 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10978,6 +10978,12 @@ self: super: with self; {
     SDL2_image = pkgs.SDL2_image_2_0;
   };
 
+  pygame-ce = callPackage ../development/python-modules/pygame-ce {
+    inherit (pkgs.darwin.apple_sdk.frameworks) AppKit;
+    SDL2_image = pkgs.SDL2_image_2_0;
+    SDL2_mixer = pkgs.SDL2_mixer_2_0;
+  };
+
   pygame-sdl2 = callPackage ../development/python-modules/pygame-sdl2 { };
 
   pygame-gui = callPackage ../development/python-modules/pygame-gui { };