diff --git a/pkgs/development/python-modules/quixote/default.nix b/pkgs/development/python-modules/quixote/default.nix
new file mode 100644
index 000000000000..557a59390fb9
--- /dev/null
+++ b/pkgs/development/python-modules/quixote/default.nix
@@ -0,0 +1,40 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchPypi,
+  pytestCheckHook,
+  pythonOlder,
+  setuptools,
+}:
+
+buildPythonPackage rec {
+  pname = "quixote";
+  version = "3.6";
+  pyproject = true;
+
+  disabled = pythonOlder "3.8";
+
+  src = fetchPypi {
+    pname = "Quixote";
+    inherit version;
+    hash = "sha256-78t6tznI3+vIRkWNi0HDPGhR8aGaET3IMXQvmAPdSSY=";
+  };
+
+  build-system = [ setuptools ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
+
+  pythonImportsCheck = [ "quixote" ];
+
+  disabledTestPaths = [
+    # Test has additional requirements
+    "quixote/ptl/test/test_ptl.py"
+  ];
+
+  meta = with lib; {
+    description = "A small and flexible Python Web application framework";
+    homepage = "https://pypi.org/project/Quixote/";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 092730d89008..8ba934720ea5 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -12899,6 +12899,8 @@ self: super: with self; {
 
   quil = callPackage ../development/python-modules/quil { };
 
+  quixote = callPackage ../development/python-modules/quixote { };
+
   qutip = callPackage ../development/python-modules/qutip { };
 
   qmk-dotty-dict = callPackage ../development/python-modules/qmk-dotty-dict { };