diff --git a/pkgs/applications/science/biology/clustal-omega/default.nix b/pkgs/applications/science/biology/clustal-omega/default.nix
new file mode 100644
index 000000000000..3464e134ee85
--- /dev/null
+++ b/pkgs/applications/science/biology/clustal-omega/default.nix
@@ -0,0 +1,32 @@
+{ stdenv, fetchurl, argtable }:
+
+stdenv.mkDerivation rec {
+  version = "1.2.4";
+  name = "clustal-omega-${version}";
+
+  src = fetchurl {
+    url = "http://www.clustal.org/omega/${name}.tar.gz";
+    sha256 = "1vm30mzncwdv881vrcwg11vzvrsmwy4wg80j5i0lcfk6dlld50w6";
+  };
+
+  buildInputs = [ argtable ];
+
+  preConfigure = ''
+    for f in configure \
+             src/clustal-omega-config.h \
+             src/clustal-omega-config.h \
+             src/config.h.in \
+             src/mymain.c
+    do
+      sed -i -re 's/argtable2/argtable3/g' $f
+    done
+  '';
+
+  meta = with stdenv.lib; {
+    description = "General purpose multiple sequence alignment program for protein and DNA/RNA";
+    homepage = http://www.clustal.org/omega/;
+    license = licenses.gpl2;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index c28665f1b61d..634b1594514f 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -22129,6 +22129,8 @@ in
 
   cmtk = callPackage ../applications/science/biology/cmtk { };
 
+  clustal-omega = callPackage ../applications/science/biology/clustal-omega { };
+
   conglomerate = callPackage ../applications/science/biology/conglomerate { };
 
   dcm2niix = callPackage ../applications/science/biology/dcm2niix { };