diff --git a/pkgs/development/python-modules/dnspython/default.nix b/pkgs/development/python-modules/dnspython/default.nix
index 40b3d7a36dec..59730bff71ec 100644
--- a/pkgs/development/python-modules/dnspython/default.nix
+++ b/pkgs/development/python-modules/dnspython/default.nix
@@ -1,4 +1,5 @@
 { lib
+, stdenv
 , buildPythonPackage
 , fetchPypi
 , pythonOlder
@@ -24,6 +25,11 @@ buildPythonPackage rec {
   disabledTests = [
     # dns.exception.SyntaxError: protocol not found
     "test_misc_good_WKS_text"
+  ] ++ lib.optionals stdenv.isDarwin [
+    # unable to get local issuer certificate
+    "test_async"
+    "test_query"
+    "test_resolver_override"
   ];
 
   nativeBuildInputs = [