diff --git a/pkgs/build-support/bintools-wrapper/ld-wrapper.sh b/pkgs/build-support/bintools-wrapper/ld-wrapper.sh
index 3bd9c68f2336..7e00d02b0374 100644
--- a/pkgs/build-support/bintools-wrapper/ld-wrapper.sh
+++ b/pkgs/build-support/bintools-wrapper/ld-wrapper.sh
@@ -226,12 +226,6 @@ if [[ "$NIX_DONT_SET_RPATH_@suffixSalt@" != 1 && "$linkType" != static-pie ]]; t
 
 fi
 
-# This is outside the DONT_SET_RPATH branch because it's more targeted and we
-# usually want it (on Darwin) even if DONT_SET_RPATH is set.
-if [ -n "${NIX_COREFOUNDATION_RPATH:-}" ]; then
-  extraAfter+=(-rpath $NIX_COREFOUNDATION_RPATH)
-fi
-
 # Only add --build-id if this is a final link. FIXME: should build gcc
 # with --enable-linker-build-id instead?
 #
diff --git a/pkgs/development/libraries/glibc/default.nix b/pkgs/development/libraries/glibc/default.nix
index 96a08178637d..b57312e63a2d 100644
--- a/pkgs/development/libraries/glibc/default.nix
+++ b/pkgs/development/libraries/glibc/default.nix
@@ -41,9 +41,6 @@ in
 
       # Apparently --bindir is not respected.
       makeFlagsArray+=("bindir=$bin/bin" "sbindir=$bin/sbin" "rootsbindir=$bin/sbin")
-    '' + lib.optionalString stdenv.buildPlatform.isDarwin ''
-      # ld-wrapper will otherwise attempt to inject CoreFoundation into ld-linux's RUNPATH
-      export NIX_COREFOUNDATION_RPATH=
     '';
 
     # The pie, stackprotector and fortify hardening flags are autodetected by
diff --git a/pkgs/os-specific/darwin/apple-sdk/default.nix b/pkgs/os-specific/darwin/apple-sdk/default.nix
index 30081c824378..1cd5afe19301 100644
--- a/pkgs/os-specific/darwin/apple-sdk/default.nix
+++ b/pkgs/os-specific/darwin/apple-sdk/default.nix
@@ -163,17 +163,6 @@ let
 
     propagatedBuildInputs = builtins.attrValues deps;
 
-    # don't use pure CF for dylibs that depend on frameworks
-    setupHook = ./framework-setup-hook.sh;
-
-    # Not going to be more specific than this for now
-    __propagatedImpureHostDeps = lib.optionals (name != "Kernel") [
-      # The setup-hook ensures that everyone uses the impure CoreFoundation who uses these SDK frameworks, so let's expose it
-      "/System/Library/Frameworks/CoreFoundation.framework"
-      "/System/Library/Frameworks/${name}.framework"
-      "/System/Library/Frameworks/${name}.framework/${name}"
-    ];
-
     meta = with lib; {
       description = "Apple SDK framework ${name}";
       maintainers = with maintainers; [ copumpkin ];
diff --git a/pkgs/os-specific/darwin/apple-sdk/framework-setup-hook.sh b/pkgs/os-specific/darwin/apple-sdk/framework-setup-hook.sh
deleted file mode 100644
index b0d5915fc1fc..000000000000
--- a/pkgs/os-specific/darwin/apple-sdk/framework-setup-hook.sh
+++ /dev/null
@@ -1,42 +0,0 @@
-# On macOS, frameworks are linked to the system CoreFoundation but
-# dynamic libraries built with nix use a pure version of CF this
-# causes segfaults for binaries that depend on it at runtime.  This
-# can be solved in two ways.
-# 1. Rewrite references to the pure CF using this setup hook, this
-# works for the simple case but this can still cause problems if other
-# dependencies (eg. python) use the pure CF.
-# 2. Create a wrapper for the binary that sets DYLD_FRAMEWORK_PATH to
-# /System/Library/Frameworks.  This will make everything load the
-# system's CoreFoundation framework while still keeping the
-# dependencies pure for other packages.
-
-fixupOutputHooks+=('fixDarwinFrameworksIn $prefix')
-
-fixDarwinFrameworks() {
-    local systemPrefix='/System/Library/Frameworks'
-
-    for fn in "$@"; do
-        if [ -L "$fn" ]; then continue; fi
-        echo "$fn: fixing dylib"
-
-        for framework in $(otool -L "$fn" | awk '/CoreFoundation\.framework/ {print $1}'); do
-          install_name_tool -change "$framework" "$systemPrefix/CoreFoundation.framework/Versions/A/CoreFoundation" "$fn" >&2
-        done
-    done
-}
-
-fixDarwinFrameworksIn() {
-    local dir="$1"
-    fixDarwinFrameworks $(find "$dir" -name "*.dylib")
-}
-
-
-# This configures the stdenv to use /System/Library/Frameworks/CoreFoundation.framework
-# instead of the nix version by including the system frameworks path
-# as an rpath entry when creating binaries.
-
-useSystemCoreFoundationFramework () {
-  export NIX_COREFOUNDATION_RPATH=/System/Library/Frameworks
-}
-
-addEnvHooks "$hostOffset" useSystemCoreFoundationFramework
diff --git a/pkgs/os-specific/darwin/swift-corelibs/corefoundation.nix b/pkgs/os-specific/darwin/swift-corelibs/corefoundation.nix
index 5c593b1488e2..0b7c85b588f2 100644
--- a/pkgs/os-specific/darwin/swift-corelibs/corefoundation.nix
+++ b/pkgs/os-specific/darwin/swift-corelibs/corefoundation.nix
@@ -86,6 +86,5 @@ stdenv.mkDerivation {
       "$out/Library/Frameworks/CoreFoundation.framework/Versions/A/CoreFoundation"
 
     mkdir -p "$out/nix-support"
-    substituteAll ${./pure-corefoundation-hook.sh} "$out/nix-support/setup-hook"
   '';
 }
diff --git a/pkgs/os-specific/darwin/swift-corelibs/pure-corefoundation-hook.sh b/pkgs/os-specific/darwin/swift-corelibs/pure-corefoundation-hook.sh
deleted file mode 100644
index d5539f50861a..000000000000
--- a/pkgs/os-specific/darwin/swift-corelibs/pure-corefoundation-hook.sh
+++ /dev/null
@@ -1,7 +0,0 @@
-usePureCoreFoundation() {
-# Avoid overriding value set by the impure CF
-    if [ -z "${NIX_COREFOUNDATION_RPATH:-}" ]; then
-        export NIX_COREFOUNDATION_RPATH=@out@/Library/Frameworks
-    fi
-}
-addEnvHooks "$hostOffset" usePureCoreFoundation