diff --git a/pkgs/development/python-modules/monai/default.nix b/pkgs/development/python-modules/monai/default.nix
new file mode 100644
index 000000000000..74ccf0b1868e
--- /dev/null
+++ b/pkgs/development/python-modules/monai/default.nix
@@ -0,0 +1,64 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pythonOlder
+, ninja
+, ignite
+, numpy
+, pybind11
+, pytorch
+, which
+}:
+
+buildPythonPackage rec {
+  pname = "monai";
+  version = "0.9.0";
+  disabled = pythonOlder "3.7";
+
+  src = fetchFromGitHub {
+    owner = "Project-MONAI";
+    repo = "MONAI";
+    rev = version;
+    sha256 = "sha256-HxW9WYxt2a7fS9/1E9DtiH+SCTTJoxYBfgZqskYdcvI=";
+  };
+
+  # Ninja is not detected by setuptools for some reason even though it's present:
+  postPatch = ''
+    substituteInPlace "setup.cfg" --replace "ninja" ""
+  '';
+
+  preBuild = ''
+    export MAX_JOBS=$NIX_BUILD_CORES;
+  '';
+
+  nativeBuildInputs = [ ninja which ];
+  buildInputs = [ pybind11 ];
+  propagatedBuildInputs = [ numpy pytorch ignite ];
+
+  BUILD_MONAI = 1;
+
+  doCheck = false;  # takes too long; numerous dependencies, some not in Nixpkgs
+
+  pythonImportsCheck = [
+    "monai"
+    "monai.apps"
+    "monai.data"
+    "monai.engines"
+    "monai.handlers"
+    "monai.inferers"
+    "monai.losses"
+    "monai.metrics"
+    "monai.optimizers"
+    "monai.networks"
+    "monai.transforms"
+    "monai.utils"
+    "monai.visualize"
+  ];
+
+  meta = with lib; {
+    description = "Pytorch framework (based on Ignite) for deep learning in medical imaging";
+    homepage = "https://github.com/Project-MONAI/MONAI";
+    license = licenses.asl20;
+    maintainers = [ maintainers.bcdarwin ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 4f430c6bb183..7276bf4309f8 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5541,6 +5541,8 @@ in {
 
   moku = callPackage ../development/python-modules/moku { };
 
+  monai = callPackage ../development/python-modules/monai { };
+
   monero = callPackage ../development/python-modules/monero { };
 
   mongomock = callPackage ../development/python-modules/mongomock { };