diff --git a/pkgs/development/ruby-modules/gem-config/default.nix b/pkgs/development/ruby-modules/gem-config/default.nix
index 36e770b05d0b..f358d47e2193 100644
--- a/pkgs/development/ruby-modules/gem-config/default.nix
+++ b/pkgs/development/ruby-modules/gem-config/default.nix
@@ -20,14 +20,14 @@
 { lib, fetchurl, fetchpatch2, writeScript, ruby, libkrb5, libxml2, libxslt, python2, stdenv, which
 , libiconv, postgresql, nodejs, clang, sqlite, zlib, imagemagick, lasem
 , pkg-config , ncurses, xapian, gpgme, util-linux, tzdata, icu, libffi
-, cmake, libssh2, openssl, openssl_1_1, libmysqlclient, git, perl, pcre, pcre2, gecode_3, curl
-, libsodium, snappy, libossp_uuid, lxc, libpcap, xorg, gtk2, gtk3, lerc, buildRubyGem
+, cmake, libssh2, openssl, openssl_1_1, libmysqlclient, git, perl, pcre2, gecode_3, curl
+, libsodium, snappy, libossp_uuid, lxc, libpcap, xorg, gtk3, lerc, buildRubyGem
 , cairo, expat, re2, rake, gobject-introspection, gdk-pixbuf, zeromq, czmq, graphicsmagick, libcxx
 , file, libvirt, glib, vips, taglib, libopus, linux-pam, libidn, protobuf, fribidi, harfbuzz
 , bison, flex, pango, python3, patchelf, binutils, freetds, wrapGAppsHook3, atk
 , bundler, libsass, dart-sass, libexif, libselinux, libsepol, shared-mime-info, libthai, libdatrie
 , CoreServices, DarwinTools, cctools, libtool, discount, exiv2, libepoxy, libxkbcommon, libmaxminddb, libyaml
-, cargo, rustc, rustPlatform
+, cargo, rustc, rustPlatform, libsysprof-capture
 , autoSignDarwinBinariesHook
 }@args:
 
@@ -71,13 +71,13 @@ in
   cairo = attrs: {
     nativeBuildInputs = [ pkg-config ]
       ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    buildInputs = [ gtk2 pcre2 xorg.libpthreadstubs xorg.libXdmcp];
+    buildInputs = [ cairo expat glib libsysprof-capture pcre2 xorg.libpthreadstubs xorg.libXdmcp ];
   };
 
   cairo-gobject = attrs: {
     nativeBuildInputs = [ pkg-config ]
       ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    buildInputs = [ cairo expat pcre2 xorg.libpthreadstubs xorg.libXdmcp ];
+    buildInputs = [ cairo expat libsysprof-capture pcre2 xorg.libpthreadstubs xorg.libXdmcp ];
   };
 
   charlock_holmes = attrs: {
@@ -257,7 +257,7 @@ in
   gio2 = attrs: {
     nativeBuildInputs = [ pkg-config gobject-introspection ]
       ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    buildInputs = [ gtk2 pcre pcre2 ] ++ lib.optionals stdenv.hostPlatform.isLinux [ util-linux libselinux libsepol ];
+    buildInputs = [ glib libsysprof-capture pcre2 ] ++ lib.optionals stdenv.hostPlatform.isLinux [ util-linux libselinux libsepol ];
   };
 
   gitlab-markup = attrs: { meta.priority = 1; };
@@ -346,29 +346,7 @@ in
   glib2 = attrs: {
     nativeBuildInputs = [ pkg-config ]
       ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    buildInputs = [ gtk2 pcre2 ];
-  };
-
-  gtk2 = attrs: {
-    nativeBuildInputs = [
-      binutils pkg-config
-    ] ++ lib.optionals stdenv.hostPlatform.isLinux [
-      util-linux libselinux libsepol
-    ] ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    propagatedBuildInputs = [
-      atk
-      gdk-pixbuf
-      fribidi
-      gobject-introspection
-      gtk2
-      harfbuzz
-      libdatrie
-      libthai
-      pcre pcre2
-      xorg.libpthreadstubs
-      xorg.libXdmcp
-    ];
-    dontStrip = stdenv.hostPlatform.isDarwin;
+    buildInputs = [ glib libsysprof-capture pcre2 ];
   };
 
   gtk3 = attrs: {
@@ -390,8 +368,8 @@ in
       harfbuzz
       lerc
       libdatrie
+      libsysprof-capture
       libthai
-      pcre
       pcre2
       xorg.libpthreadstubs
       xorg.libXdmcp
@@ -403,9 +381,9 @@ in
   };
 
   gobject-introspection = attrs: {
-    nativeBuildInputs = [ pkg-config pcre2 ]
+    nativeBuildInputs = [ pkg-config ]
       ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    propagatedBuildInputs = [ gobject-introspection wrapGAppsHook3 glib ];
+    propagatedBuildInputs = [ gobject-introspection wrapGAppsHook3 glib pcre2 libsysprof-capture ];
   };
 
   gollum = attrs: {
@@ -653,15 +631,10 @@ in
   pango = attrs: {
     nativeBuildInputs = [
       pkg-config
-      fribidi
-      harfbuzz
-      pcre pcre2
-      xorg.libpthreadstubs
-      xorg.libXdmcp
     ] ++ lib.optionals stdenv.hostPlatform.isDarwin [ DarwinTools ];
-    buildInputs = [ libdatrie libthai ]
+    buildInputs = [ libdatrie libthai fribidi harfbuzz libsysprof-capture pcre2 xorg.libpthreadstubs xorg.libXdmcp ]
       ++ lib.optionals stdenv.hostPlatform.isLinux [ libselinux libsepol util-linux ];
-    propagatedBuildInputs = [ gobject-introspection wrapGAppsHook3 gtk2 ];
+    propagatedBuildInputs = [ gobject-introspection wrapGAppsHook3 ];
   };
 
   patron = attrs: {