diff --git a/pkgs/development/interpreters/python/cpython/default.nix b/pkgs/development/interpreters/python/cpython/default.nix
index 73197f065625..ddf0a5548475 100644
--- a/pkgs/development/interpreters/python/cpython/default.nix
+++ b/pkgs/development/interpreters/python/cpython/default.nix
@@ -115,7 +115,7 @@ let
   ] ++ optionals (stdenv.hostPlatform != stdenv.buildPlatform) [
     buildPackages.stdenv.cc
     pythonForBuild
-  ] ++ optionals (stdenv.cc.isClang && (enableLTO || enableOptimizations)) [
+  ] ++ optionals (stdenv.cc.isClang && (!stdenv.hostPlatform.useAndroidPrebuilt or false) && (enableLTO || enableOptimizations)) [
     stdenv.cc.cc.libllvm.out
   ];