diff --git a/pkgs/tools/misc/esptool/default.nix b/pkgs/tools/misc/esptool/default.nix
index a62e266874d6..9efa31d36537 100644
--- a/pkgs/tools/misc/esptool/default.nix
+++ b/pkgs/tools/misc/esptool/default.nix
@@ -1,29 +1,19 @@
 { lib
 , fetchFromGitHub
-, fetchpatch
 , python3
 }:
 
 python3.pkgs.buildPythonApplication rec {
   pname = "esptool";
-  version = "4.4";
+  version = "4.5";
 
   src = fetchFromGitHub {
     owner = "espressif";
     repo = "esptool";
     rev = "v${version}";
-    hash = "sha256-haLwf3loOvqdqQN/iuVBciQ6nCnuc9AqqOGKvDwLBHE=";
+    hash = "sha256-SwMdemCk3e3RyXTzoXIqDRywpg3ogE9nQjXGBz0BjwE=";
   };
 
-  patches = [
-    ./test-call-bin-directly.patch
-    (fetchpatch {
-      name = "bitstring-4-compatibility.patch";
-      url = "https://github.com/espressif/esptool/commit/ee27a6437576797d5f58c31e1c39f3a232a71df0.patch";
-      hash = "sha256-8/AzR3HK79eQQRSaGEKU4YKn/piPCPjm/G9pvizKuUE=";
-    })
-  ];
-
   propagatedBuildInputs = with python3.pkgs; [
     bitstring
     cryptography
@@ -34,19 +24,18 @@ python3.pkgs.buildPythonApplication rec {
 
   nativeCheckInputs = with python3.pkgs; [
     pyelftools
-    pytest
+    pytestCheckHook
   ];
 
   # tests mentioned in `.github/workflows/test_esptool.yml`
   checkPhase = ''
     runHook preCheck
 
-    export ESPSECURE_PY=$out/bin/espsecure.py
-    export ESPTOOL_PY=$out/bin/esptool.py
-    ${python3.interpreter} test/test_imagegen.py
-    ${python3.interpreter} test/test_espsecure.py
-    ${python3.interpreter} test/test_merge_bin.py
-    ${python3.interpreter} test/test_modules.py
+    pytest test/test_imagegen.py
+    pytest test/test_espsecure.py
+    pytest test/test_merge_bin.py
+    pytest test/test_image_info.py
+    pytest test/test_modules.py
 
     runHook postCheck
   '';
diff --git a/pkgs/tools/misc/esptool/test-call-bin-directly.patch b/pkgs/tools/misc/esptool/test-call-bin-directly.patch
deleted file mode 100644
index b7d772780090..000000000000
--- a/pkgs/tools/misc/esptool/test-call-bin-directly.patch
+++ /dev/null
@@ -1,89 +0,0 @@
-diff --git a/test/test_espsecure.py b/test/test_espsecure.py
-index 25b0b87..627005c 100755
---- a/test/test_espsecure.py
-+++ b/test/test_espsecure.py
-@@ -35,7 +35,7 @@ class EspSecureTestCase:
-         Returns output as a string if there is any,
-         raises an exception if espsecure.py fails
-         """
--        cmd = [sys.executable, ESPSECURE_PY] + args.split(" ")
-+        cmd = [ESPSECURE_PY] + args.split(" ")
-         print("\nExecuting {}...".format(" ".join(cmd)))
- 
-         try:
-diff --git a/test/test_esptool.py b/test/test_esptool.py
-index 042a1ce..b294e26 100755
---- a/test/test_esptool.py
-+++ b/test/test_esptool.py
-@@ -57,7 +57,10 @@ try:
-     ESPTOOL_PY = os.environ["ESPTOOL_PY"]
- except KeyError:
-     ESPTOOL_PY = os.path.join(TEST_DIR, "..", "esptool/__init__.py")
--ESPSECURE_PY = os.path.join(TEST_DIR, "..", "espsecure/__init__.py")
-+try:
-+    ESPSECURE_PY = os.environ["ESPSECURE_PY"]
-+except KeyError:
-+    ESPSECURE_PY = os.path.join(TEST_DIR, "..", "espsecure/__init__.py")
- ESPRFC2217SERVER_PY = os.path.join(TEST_DIR, "..", "esp_rfc2217_server.py")
- 
- RETURN_CODE_FATAL_ERROR = 2
-@@ -74,7 +77,6 @@ class ESPRFC2217Server(object):
-     def __init__(self, rfc2217_port=None):
-         self.port = rfc2217_port or self.get_free_port()
-         self.cmd = [
--            sys.executable,
-             ESPRFC2217SERVER_PY,
-             "-p",
-             str(self.port),
-@@ -130,7 +132,7 @@ class ESPRFC2217Server(object):
- class EsptoolTestCase:
-     def run_espsecure(self, args):
- 
--        cmd = [sys.executable, ESPSECURE_PY] + args.split(" ")
-+        cmd = [ESPSECURE_PY] + args.split(" ")
-         print("\nExecuting {}...".format(" ".join(cmd)))
-         try:
-             output = subprocess.check_output(
-@@ -155,7 +157,7 @@ class EsptoolTestCase:
-         Raises an exception if esptool.py fails.
-         """
-         trace_args = ["--trace"] if arg_trace else []
--        cmd = [sys.executable, ESPTOOL_PY] + trace_args
-+        cmd = [ESPTOOL_PY] + trace_args
-         if chip_name or arg_chip is not None and chip_name != "auto":
-             cmd += ["--chip", chip_name or arg_chip]
-         if rfc2217_port or arg_port is not None:
-diff --git a/test/test_imagegen.py b/test/test_imagegen.py
-index a1feec2..01bd59c 100755
---- a/test/test_imagegen.py
-+++ b/test/test_imagegen.py
-@@ -108,7 +108,7 @@ class BaseTestCase:
-         Run esptool.py image_info on a binary file,
-         assert no red flags about contents.
-         """
--        cmd = [sys.executable, ESPTOOL_PY, "--chip", chip, "image_info", binpath]
-+        cmd = [ESPTOOL_PY, "--chip", chip, "image_info", binpath]
-         try:
-             output = subprocess.check_output(cmd)
-             output = output.decode("utf-8")
-@@ -123,7 +123,7 @@ class BaseTestCase:
- 
-     def run_elf2image(self, chip, elf_path, version=None, extra_args=[]):
-         """Run elf2image on elf_path"""
--        cmd = [sys.executable, ESPTOOL_PY, "--chip", chip, "elf2image"]
-+        cmd = [ESPTOOL_PY, "--chip", chip, "elf2image"]
-         if version is not None:
-             cmd += ["--version", str(version)]
-         cmd += [elf_path] + extra_args
-diff --git a/test/test_merge_bin.py b/test/test_merge_bin.py
-index 8230069..2df5f8c 100755
---- a/test/test_merge_bin.py
-+++ b/test/test_merge_bin.py
-@@ -39,7 +39,6 @@ class TestMergeBin:
-             output_file.close()
- 
-             cmd = [
--                sys.executable,
-                 ESPTOOL_PY,
-                 "--chip",
-                 chip,