diff --git a/nixos/doc/manual/release-notes/rl-2003.xml b/nixos/doc/manual/release-notes/rl-2003.xml
index 860cb72bbf62..606add95f30b 100644
--- a/nixos/doc/manual/release-notes/rl-2003.xml
+++ b/nixos/doc/manual/release-notes/rl-2003.xml
@@ -757,6 +757,12 @@ auth required pam_succeed_if.so uid >= 1000 quiet
      </warning>
     </para>
    </listitem>
+   <listitem>
+     <para>
+       The TokuDB storage engine will be disabled in <package>mariadb</package> 10.5. It is recommended to switch
+       to RocksDB. See also <link xlink:href="https://mariadb.com/kb/en/tokudb/">TokuDB</link>.
+     </para>
+   </listitem>
   </itemizedlist>
  </section>
 
diff --git a/pkgs/servers/sql/mariadb/default.nix b/pkgs/servers/sql/mariadb/default.nix
index 2b287c8f6ffd..1e9c087bb6e7 100644
--- a/pkgs/servers/sql/mariadb/default.nix
+++ b/pkgs/servers/sql/mariadb/default.nix
@@ -1,9 +1,10 @@
 { stdenv, fetchurl, fetchFromGitHub, cmake, pkgconfig, makeWrapper, ncurses, zlib, xz, lzo, lz4, bzip2, snappy
 , libiconv, openssl, pcre, boost, judy, bison, libxml2, libkrb5, linux-pam, curl
-, libaio, libevent, jemalloc, cracklib, systemd, perl
+, libaio, libevent, jemalloc450, jemalloc, cracklib, systemd, perl
 , fixDarwinDylibNames, cctools, CoreServices, less
 , numactl # NUMA Support
 , withStorageMroonga ? true, kytea, msgpack, zeromq
+, withStorageToku ? true
 }:
 
 with stdenv.lib;
@@ -34,9 +35,11 @@ common = rec { # attributes common to both builds
   nativeBuildInputs = [ cmake pkgconfig ];
 
   buildInputs = [
-    ncurses openssl zlib pcre jemalloc libiconv curl
+    ncurses openssl zlib pcre libiconv curl
   ] ++ optionals stdenv.hostPlatform.isLinux [ libaio systemd libkrb5 ]
-    ++ optionals stdenv.hostPlatform.isDarwin [ perl fixDarwinDylibNames cctools CoreServices ];
+    ++ optionals stdenv.hostPlatform.isDarwin [ perl fixDarwinDylibNames cctools CoreServices ]
+    ++ optional (!stdenv.hostPlatform.isDarwin && withStorageToku) [ jemalloc450 ]
+    ++ optional (!stdenv.hostPlatform.isDarwin && !withStorageToku) [ jemalloc ];
 
   prePatch = ''
     sed -i 's,[^"]*/var/log,/var/log,g' storage/mroonga/vendor/groonga/CMakeLists.txt
@@ -80,8 +83,6 @@ common = rec { # attributes common to both builds
     # to pass in java explicitly.
     "-DCONNECT_WITH_JDBC=OFF"
     "-DCURSES_LIBRARY=${ncurses.out}/lib/libncurses.dylib"
-  ] ++ optionals stdenv.hostPlatform.isMusl [
-    "-DWITHOUT_TOKUDB=1" # mariadb docs say disable this for musl
   ];
 
   postInstall = ''
@@ -99,6 +100,7 @@ common = rec { # attributes common to both builds
   passthru.mysqlVersion = "5.7";
 
   meta = {
+
     description = "An enhanced, drop-in replacement for MySQL";
     homepage    = https://mariadb.org/;
     license     = licenses.gpl2;
@@ -166,10 +168,13 @@ server = stdenv.mkDerivation (common // {
   ] ++ optional (stdenv.hostPlatform.isLinux && !stdenv.hostPlatform.isAarch32) [
     "-DWITH_NUMA=ON"
   ] ++ optional (!withStorageMroonga) [
-    "-DWITHOUT_MROONGA=ON"
-  ] ++ optionals stdenv.hostPlatform.isDarwin [
-    "-DWITHOUT_OQGRAPH=1"
+    "-DWITHOUT_MROONGA=1"
+  ] ++ optional (stdenv.hostPlatform.isDarwin || stdenv.hostPlatform.isMusl || !withStorageToku) [
     "-DWITHOUT_TOKUDB=1"
+  ] ++ optional (!stdenv.hostPlatform.isDarwin && withStorageToku) [
+    "-DWITH_JEMALLOC=static"
+  ] ++ optional stdenv.hostPlatform.isDarwin [
+    "-DWITHOUT_OQGRAPH=1"
   ];
 
   preConfigure = optionalString (!stdenv.hostPlatform.isDarwin) ''
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index e5a0e81f4a76..ab04c59ee42c 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -15771,7 +15771,7 @@ in
   mariadb = callPackage ../servers/sql/mariadb {
     # As per mariadb's cmake, "static jemalloc_pic.a can only be used up to jemalloc 4".
     # https://jira.mariadb.org/browse/MDEV-15034
-    jemalloc = jemalloc450.override ({ disableInitExecTls = true; });
+    jemalloc450 = jemalloc450.override ({ disableInitExecTls = true; });
     inherit (darwin) cctools;
     inherit (pkgs.darwin.apple_sdk.frameworks) CoreServices;
   };